On-demand treatment that helps you fight back
Actor portrayal.
For US Residents Only
INBRIJA, the on-demand inhaled levodopa,
may start to work in as little as 10 minutes
For people taking carbidopa/levodopa for Parkinson's disease (PD) and experiencing
the return of symptoms between regular doses of medication, adding INBRIJA can help.
In a large clinical trial, INBRIJA started improving motor symptoms in as early as 10 minutes
and significant relief in motor symptoms was seen in 30 minutes of taking INBRIJA.
Rescue the moments in your day with INBRIJA
INBRIJA is an inhaled form of the levodopa in your regular carbidopa/levodopa PD medication. INBRIJA does not replace your regular carbidopa/levodopa medicine.
You can use INBRIJA as needed* to fight Parkinson's symptoms when they return.
*1 dose (2 capsules) per OFF
period up to 5 times per day.
Jimmy uses INBRIJA where
he wants to use it...
Jimmy uses INBRIJA where he wants to use it...
I’ve been using it a couple of years now and I’ll do it in front of anybody, in a restaurant or anywhere. And it’s allowed me to have Parkinson’s and still be able to go out… 
—Jimmy, person with Parkinson's
Please see Full Prescribing Information
INBRIJA can help you manage the return of your symptoms
INBRIJA is used in addition to your usual Parkinson's medications. It may start to work in as
little as 10 minutes. In a large study, significant relief in motor symptoms was seen in
30 minutes of taking INBRIJA.
INBRIJA is orally inhaled.
- INBRIJA is inhaled levodopa, so it goes through your lungs and is absorbed faster than oral
carbidopa/levodopa- Before using INBRIJA, tell your healthcare provider if you have asthma, chronic obstructive
pulmonary disease (COPD), or any chronic lung disease - Tell your healthcare provider if you experience bronchospasm. People with asthma, COPD,
or other lung diseases may wheeze or have difficulty breathing after inhaling INBRIJA. If this
occurs, stop taking INBRIJA and seek immediate medical attention
- Before using INBRIJA, tell your healthcare provider if you have asthma, chronic obstructive
- INBRIJA is inhaled levodopa, so it goes through your lungs and is absorbed faster than oral carbidopa/levodopa
- Before using INBRIJA, tell your healthcare provider if you have asthma, chronic obstructive
pulmonary disease (COPD), or any chronic lung disease - Tell your healthcare provider if you experience bronchospasm. People with asthma, COPD,
or other lung diseases may wheeze or have difficulty breathing after inhaling INBRIJA. If this
occurs, stop taking INBRIJA and seek immediate medical attention
- Before using INBRIJA, tell your healthcare provider if you have asthma, chronic obstructive
- INBRIJA is used in addition to your regular carbidopa/levodopa (CD/LD) medication. INBRIJA
does not replace your regular CD/LD medicines. Use it when your regular PD medications
aren't working as expected and your symptoms return - Going through the lungs means that absorption of the medicine is not affected by meals or
other conditions in your gut
INBRIJA is for use as needed
Take it as prescribed when your symptoms return (OFF periods). Use 1 dose (2 capsules) per OFF period and no more than 5 doses (10 capsules) per day.
INBRIJA is lightweight and portable
INBRIJA is easy to carry with you. Store your INBRIJA at room temperature 68°F to 77°F (20 °C to 25 °C) in a dry place.
Keep the capsules in their foil (blister) packages until just before you're ready to use them.
Talk to your doctor about a $0 initial co-pay† for INBRIJA
†Limitations and restrictions apply.INBRIJA® (levodopa inhalation powder) IMPORTANT CONSUMER SAFETY INFORMATION
What is INBRIJA?
INBRIJA is an inhaled levodopa prescription medicine used to treat the return of Parkinson’s symptoms (known as OFF episodes) in people with Parkinson’s disease who are treated with carbidopa/levodopa medicines. INBRIJA does not replace regular carbidopa/levodopa medicine. It is not known if INBRIJA is safe or effective in children.
Do not use INBRIJA if you: take or have taken a nonselective monoamine oxidase inhibitor such as phenelzine or tranylcypromine within the last 2 weeks.
Before using INBRIJA, tell your healthcare provider about your medical conditions, including if you:
- have asthma, chronic obstructive pulmonary disease (COPD), or any chronic lung disease
- have daytime sleepiness, sleep disorders, sleepiness/drowsiness without warning, or use medicine that increases sleepiness, including antidepressants or antipsychotics
- have dizziness, nausea, sweating, or fainting when standing up
- have abnormal movement (dyskinesia)
- have mental health problems such as hallucinations or psychosis
- have uncontrollable urges like gambling, sexual urges, spending money, or binge eating
- have glaucoma
- are pregnant or plan to become pregnant. It is unknown if INBRIJA can harm your unborn baby.
- are breastfeeding or plan to breastfeed. Levodopa can pass into breastmilk and it is unknown if it can harm the baby.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Using INBRIJA and certain other medicines may affect each other and cause serious side effects. Especially tell your healthcare provider if you take:
- MAO-B inhibitors
- dopamine (D2) antagonists (including phenothiazines, butyrophenones, risperidone, metoclopramide)
- isoniazid
- iron salts or multivitamins that contain iron salts
How should I use INBRIJA?
INBRIJA is for oral inhalation use only. Do not swallow or open INBRIJA capsules. Only use INBRIJA capsules with the INBRIJA inhaler. Do not use the INBRIJA inhaler to take any other medicine.
Do not orally inhale more than 1 dose (2 capsules) for any OFF period. Do not take more than 5 doses (10 capsules) in a day.
What should I avoid while taking INBRIJA?
Do not drive, operate machinery, or do other activities until you know how INBRIJA affects you. Sleepiness and falling asleep suddenly can happen as late as a year after treatment is started.
What are the possible Side Effects of INBRIJA?
INBRIJA can cause serious side effects including:
- falling asleep during normal daily activities with or without warning. If you become drowsy, do not drive or do activities where you need to be alert for your safety or the safety of others. Chances of falling asleep during normal activities increases if you take medicine that cause drowsiness.
- withdrawal-emergent hyperpyrexia and confusion (fever, stiff muscles, or changes in breathing and heartbeat) if you suddenly stop using INBRIJA or carbidopa/levodopa, or suddenly lower your dose of carbidopa/levodopa.
- low blood pressure when standing up (that may or may not happen with dizziness, fainting, nausea, and sweating). Get up slowly after sitting/lying down.
- hallucinations and other psychosis - INBRIJA may cause or worsen seeing/hearing/believing things that are not real; confusion, disorientation, or disorganized thinking; trouble sleeping; dreaming a lot; being overly suspicious or feeling people want to harm you; acting aggressive; and feeling agitated/restless.
- unusual uncontrollable urges such as gambling, binge eating, shopping, and sexual urges has occurred in some people using medicine like INBRIJA.
- uncontrolled, sudden body movements (dyskinesia) may be caused or worsened by INBRIJA. INBRIJA may need to be stopped or other Parkinson's medicines may need to be changed.
- bronchospasm - people with asthma, COPD, or other lung diseases may wheeze or have difficulty breathing after inhaling INBRIJA. If this occurs, stop taking INBRIJA and seek immediate medical attention.
- increased eye pressure in patients with glaucoma. Your healthcare provider should monitor this.
- changes in certain lab values including liver tests.
The most common side effects of INBRIJA are cough, upper respiratory tract infection, nausea, and change in the color of saliva or spit. Another side effect of INBRIJA is sensation of choking right after use.
These are not all the possible side effects of INBRIJA
- Call your doctor for medical advice about side effects.
- You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
The risk information provided here is not comprehensive. To learn more:
- Talk to your health care provider or pharmacist.
- Visit www.inbrija.com to obtain the Full Prescribing Information, Patient Information, and Instructions for Use.
- Call 1-800-367-5109
INBRIJA® Indication
Treats OFF periods in adults taking carbidopa/levodopa (CD/LD). INBRIJA doesn't replace CD/LD.
Important Safety Information
Don't use if you have taken a nonselective monoamine oxidase inhibitor (eg, phenelzine, tranylcypromine) within the last 2 weeks.
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